When it works
Typically within 2–3 days.
AbobotulinumtoxinA
A prescription injection that temporarily relaxes muscles to soften the frown lines, or "11s," between the eyebrows.
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FDA-approved cosmetic use for adults younger than 65




A prescription injection that temporarily relaxes muscles to soften the frown lines, or "11s," between the eyebrows. Its FDA-approved cosmetic use is for adults younger than 65.
All three soften expression lines without adding volume. No single brand is best for everyone, and their dosing units are not interchangeable. A medical consultation helps determine the right option for you.
Typically within 2–3 days.
Up to five months; results vary.
Patients may prefer its onset, previous results, or total treatment cost. Its formulation and dosing differ from Botox and Xeomin. It should not be used by anyone with a cow's milk protein allergy.

Units are not interchangeable between brands. All three soften expression lines without adding volume. No single brand is best for everyone, and their dosing units are not interchangeable.
| Product | FDA-approved cosmetic areas | When it works | How long it lasts | Good to know |
|---|---|---|---|---|
| Botox® Cosmetic OnabotulinumtoxinA |
Forehead lines, Frown lines (11s), Crow's feet, Neck bands (by consultation) | Improvement may begin within 24–48 hours and continues developing over the following weeks. | Up to four months; results vary. | Patients may prefer its familiar brand, previous results, or broader range of FDA-approved cosmetic treatment areas. |
| Dysport® AbobotulinumtoxinA |
Frown lines (11s) between the eyebrows | Typically within 2–3 days. | Up to five months; results vary. | Patients may prefer its onset, previous results, or total treatment cost. Its formulation and dosing differ from Botox and Xeomin. It should not be used by anyone with a cow's milk protein allergy. |
| Xeomin® IncobotulinumtoxinA |
Forehead lines, Frown lines (11s), Crow's feet | Typically within 2–7 days. | Generally three to four months; results vary. | Patients may prefer its formulation, which contains the active toxin without accessory proteins, or their previous results. This formula does not guarantee better results than other brands. |
Up to five months; results vary.
Its FDA-approved cosmetic use is for adults younger than 65, and it should not be used by anyone with a cow's milk protein allergy.
No. Its formulation and dosing differ from Botox and Xeomin, so units are not interchangeable.
FDA-approved cosmetic use is for adults younger than 65. It should not be used by anyone with a cow's milk protein allergy. Prescription medication; results vary.
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